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Additionally, iron chelating agents, including chloroiodohydroxyquine and its derivatives, as well as antioxidants, have shown efficacy in animal models of AD, though clinical trials are yet to be conducted (27,106,116)

To address it, it is essential for scientific research to focus on the understanding the underlying causes of PD, the mechanisms of neuronal death, and the identification of new therapeutic targets

Inhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damage

Refrigerate at 2-8C, protect from light and heat, track the beyond-use window, and avoid freeze-thaw cycling

14 The key lies in finding the sweet spot
There is a recognized need for the development, testing, and understanding of new agents or treatment modalities for depression that offer improved characteristics compared to existing antidepressants
