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The conclusion is that the trispecific SAR442257 operates via dual targeting of CD38 and CD28 on myeloma cells and of CD3 and CD28 on T lymphocytes, showing superior MM killing compared to bispecific antibodies
[DOI] [PubMed] [Google Scholar] Spradlin J

This is more critical for those on high doses or for a long time

[3] Lee JO, Kim Y, Lee JM, Suk JM, Jung I, Choi SY, Yoo KH, Seok J, Kim BJ

Huang Y

Often called the bodys master antioxidant, it not only protects cells from oxidative stress but also helps regenerate other antioxidants, enhancing overall cellular defence
