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To detect cytosolic and mitochondrial ROS, the cells (5 10 5 ) that were seeded in 60-mm dishes with indicated treatments were prepared and stained with MitoSox (5 M

VPA poisoning is responsible for central nervous system manifestations ranging from ataxia, sedation and lethargy to coma, respiratory depression, seizures and intracranial hypertension [3]

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Its mechanism involves supporting acetylcholine synthesis and helping remove toxic compounds to alleviate mitochondrial dysfunction associated with degeneration of brain structures [2][15]

2015 Nov 27;16(12):28194-217

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