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Lipoprotein lipase (LPL) is a secreted enzyme that is active in the capillaries, where it hydrolyzes triglycerides found in chylomicrons and very low-density lipoproteins (VLDL) to release FFA, which are transported across the capillary endothelial membrane as a source of energy 1

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The work provides multi-faceted proof-of-concept for the potential clinical application of lipophagy-based therapies

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