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-Elemene induces apoptosis and autophagy in colorectal cancer cells through regulating the ROS/AMPK/mTOR pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Sengupta R., Holmgren A

doi: 10.1080/1071576021000006581 35 KirlyL.KnstlerA.FattingerM.HllerK.JuhszC.MllerM.et al

the chloroacetamide portion of the RSL3 structure was essential for its bioactivity

After 5 min, transformation to cyanmethemoglobin is complete at room temperature

Common adverse effects include tachycardia, arrhythmias, and hypertension, and use is contraindicated in patients with idiopathic hypertrophic subaortic stenosis (IHSS), requiring careful monitoring during therapy