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Warning: Risk of Thyroid C-Cell Tumors In studies with mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused thyroid tumors, including thyroid cancer

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The interaction between the two is calibrated at intake to ensure they are working on complementary rather than overlapping pathways
Therefore, normal glomerular levels of HS are necessary for renal function in general and the control of glomerular permeability in particular (93, 108), and HS in small arterioles is necessary for the appropriate control of GFR (96) because it helps maintain the normal structure and function of blood vessels

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