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It is found in the heart muscle (myocardium), the valves that control blood flow, and the walls of your arteries and veins

If hepatic function becomes compromised beyond a certain level, the only effective treatment is liver transplantation

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Additionally, it has a short half-life (~ 7 days), which may contribute to higher rates of treatment failure [54, 55]

This review provides insight into the potential development of antitumor strategies to promote the controlled release of gas molecules on-demand for the effective eradication of tumor tissues

Topical retinoic acid for melasma in black patients: a vehicle controlled clinical trial Arch Dermatol