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After stopping the offending drug without improvement of renal function over 4 weeks, the patient received eculizumab resulting in improvement and stabilization of kidney function

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Furthermore, immunostaining for Ki67 and Tunel labeling at P22 revealed that mutant follicles at this stage still sustain the proliferative state of the matrix, demonstrating that P22 in the double mutant is a genuinely late anagen stage (Supplementary Fig

doi: 10.1093/jnci/89.11.803

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