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The Guidelines are not intended as a substitute for the advice or professional judgment of a health care professional, nor are they intended to be the only approach to the management of clinical problem

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Therefore, the methylation of NA is not only relevant to the abundance of free NAD + but is also relevant to the activity of these NAD + -consuming enzymes, because as a metabolite of these NAD + -consuming reactions, NA naturally has inhibitive effects on these enzymes

Gastrointestinal Problems Gastrointestinal health issues are another major side effect of vitamin B12

In the absence of, can cause folic acid deficiency, and the resulting DNA synthesis disorder that affects red blood cell development and maturation

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