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Adjustment Criteria: Decisions on treatment changes depend on the initial deficiency level, neurological symptoms, and how well the patient responds

Some may experience headache, fever, nausea, diarrhea, or fatigue with larger B12 doses

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[DOI] [PMC free article] [PubMed] [Google Scholar] 228.Erd F, Hashimoto N, Karvaly G, Nakamichi N, Kato Y

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In the early phase, within the first week of treatment, oligodendrocyte death can be observed as early as two days after treatment begins