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Higher concentrations of ROS accelerated the release of bFGF from the hydrogel in vitro, and the therapeutic effects of the ROS-responsive hydrogel loaded with bFGF were validated using mouse and pig models of ischemiareperfusion injury [337]

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Oocytes treated with 0.1 mM Epitalon showed significantly improved MMP compared to untreated aged oocytes, demonstrating that Epitalon preserves mitochondrial function during in vitro aging

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