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Besides, some other potential targets are also listed in this manuscript (Table 2)

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Van Lenten BJ, Hama SY, de Beer FC, Stafforini DM, McIntyre TM, Prescott SM, La Du BN, Fogelman AM, Navab M

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A study by Desai B et al (2024) found that significant improvements in different domains such as pain, functionality in sports and leisure as well as activities in daily living over 2 years were seen in those who underwent a single stage allograft matrix implantation.33 Allograft matrices provide a reliable option for cartilage repair, especially in larger defects or cases where autologous grafts are limited

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For example, halogenated cysteine S-conjugates can generate highly reactive thiol-containing fragments through the action of cysteine S-conjugate b-lyases: where RSH is the thiol form of the xenobiotic, which can be toxic

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Jiang, X., Charlat, O., Zamponi, R., Yang, Y

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Additionally, the elderly population may have decreased absorption or utilization of dietary vitamin B6, making supplementation a viable option

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