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the rats were then sacrificed

trans-Platinum(II) complexes with heteroaromatic ligands Substitution of the ammine ligand(s) in trans -diamminedichloroplatinum(II) with bulky, planar N-donor ligands affords trans -platinum(II) complexes with high in vitro cytotoxicity, equivalent to their corresponding cis -isomers and cisplatin

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doi: 10.1016/j.jcis.2023.10.037
FTLD, Frontotemporal lobar degeneration

There is need for a larger trial that would bring this work to the fore as a potential best practice and reveal any categories of greater effectiveness