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After fulfilling its synaptic function, glutamate is cleared from the synaptic cleft by high-affinity excitatory amino acid transporters (EAATs) located on neurons and glial cells

Thymosin Beta 4 Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-lle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-LysThr-Glu-Thr-Gin-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thy-lleGlu-Gin-Glu-Lys-Gin-Ala-Gly-Glu-Ser Sources Deek SA

In a study of 69 type 2 diabetic patients, the combination of BBR with silymarin (a known P-gp inhibitor) resulted in a more significant reduction in HbA1c compared to BBR alone [166]

One common oxidative DNA lesion is 8-hydroxydeoxyguanosine (8-OHdG), which results from the interaction of ROS with guanine bases [97]

Although previous studies emphasized that N -glycans contribute to A accumulation, the neuroprotective effects of other glycan types on AD have been ignored