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Interestingly, genetic enhancement of PPP activity and treatment with NADPH have been reported to reduce stroke-related brain damage in rodents and nonhuman primates (Li et al., 2014, 2016)

4.4 Epigenetic and protein-stabilization mechanisms Emerging research reveals that riboflavin, through its FAD cofactor, participates in several epigenetic regulatory mechanisms

Iqbal N, Azar D, Yun YM, Ghausi O, Ix J, Fitzgerald RL

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