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The second enzyme that requires vitamin B12, L-methyl-malonylcoenzyme A mutase, utilizes deoxyadenosylcobalamin to convert L-methylmalonyl-coenzyme A to succinyl-coenzyme A, a reaction involved in the metabolism of branch chain amino acids and odd chain fatty acids

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[17] [18] Cognitive Behavioral Therapy (CBT) has a strong record of effectively managing depression