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Sufficient nutrient availability continues to be required for motility, DNA quality and fertilization ability
Furthermore, METTL3 accelerated IKE- and cystine deprivation-induced ferroptosis of HASMCs[3]
TM16-TM17 of MRP1 are essential for the stimulated transport of GSH and collateral sensitivity Since MRP1/MRP2 chimeras were differently impacted in their activities of resistance to drugs co-transported with GSH, we therefore looked at the persistence or disappearance of the activity of the stimulated transport of GSH and collateral sensitivity of the FlpIn 293 expressing MRP1, MRP2 or the chimera to CS agents including verapamil, a well-established CS agent we used as a reference compound
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For the best performance, typical imaging time should be 6 cells were analysed for each imaging experiment, and all the imaging experiments were repeated at least twice with one set of representative data shown in each figure