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Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant solid tumours, and abnormal metabolic reprogramming in the tumour microenvironment is regarded as an important contributo...

In the course of HIE, a number of mitochondrial functions may be impaired, including inhibition of the respiratory chain, increased production of reactive oxygen species (ROS), loss of mitochondrial membrane potential, or activation of apoptotic pathways

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