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The generation of FXN antisense transcript 1 (FAST-1) has been associated with gene silencing mechanisms in FRDA patients, as evidence suggests that FAST-1 is not detected in unaffected individuals (Hahn et al., 2010)
Moreover, AX enhances metabolic flexibility and oxidative efficiency when combined with endurance training [52]
Moreira da Silva Guimares S, de Souza Cruz WM, de Souza Weigert G, Scalco FB, Colafranceschi AS, Ribeiro MG, et al
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That means theres no guarantee that the actual content of HCA in your supplements will match the HCA content on the label
doi: 10.1038/nature14221 6 MayersJRVander HeidenMG
