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Oxidative stress occurs when there is an imbalance between reactive oxygen species (ROS) and/or reactive nitrogen species and antioxidant capacity

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Collectively, these findings show that G6PDH is necessary in chondrocytes to maintain NADPH-mediated GSSG recycling and redox homeostasis to prevent oxidative stress and cell death, especially during chondrocyte differentiation in the hypoxic centre of the growth plate (Fig

2025B03J0092) and Science and Technology Program of Guangzhou (grant no

[DOI] [PubMed] [Google Scholar] 93.Meyer-Hoffert U., Schrder J.M