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Western populations are uncommonly affected by severe niacin deficiency that results in pellagra, but individuals at risk of pellagra may have suboptimal niacin intake, such as cancer patients and those exposed to genotoxic agents such as ionizing radiation, ultraviolet radiation, and alkylating agents [444]

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Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression

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