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By boosting these neurotransmitters, tesofensine may help brain cells communicate better

While the percent reduction in fat mass was approximately three times greater than the reduction in lean mass, the reduction in lean mass reported is typically observed over a decade or more in elderly patients (138)

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The two medications work through entirely different pharmacological pathwaysescitalopram affects central serotonin neurotransmission, whilst semaglutide acts primarily on GLP-1 receptors in the gut and brain