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Studie: Diese Studie zeigte, dass die Supplementierung mit Niacin (50 mg/kg/Tag) bei Ratten die durch Methylquecksilber induzierte berproduktion von reaktiven Sauerstoffspezies (ROS) und die Oxidation von Glutathion (GSH) in Lebermitochondrien reduzierte, was auf eine schtzende Wirkung von Niacin gegen oxidativen Stress hinweist

The treated mice resisted diet-induced obesity, showing lower fat accumulation and better glucose control, which implies MOTS-c can counteract the negative effects of a high-fat diet on weight gain and insulin action

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IsoNet, an isotopologue similarity networking strategy based on mass spectrometry-resolved stable-isotope tracing metabolomics, enables ab initio elucidation of unknown metabolites and their reactions, which is applied to the glutathione metabolic reaction network.