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Activation of NRF2 can upregulate antioxidant genes such as heme oxygenase-1 (HO-1) and inhibit ferroptosis
doi: 10.3389/fpsyt.2019.00207 41 JonesKSParkingtonDABourassaMWCeramiCKoulmanA

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Good hydration is critical here without adequate water intake, kidney function is compromised

Frontotemporal Dementia and Glucose Metabolism