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While these observations provide insight into potential mechanisms, their translation to human cardiovascular outcomes has not been fully established

Stone, K.R., et al

Inflammatory cytokines secreted in the inflammatory area, such as granulocyte-macrophage colony stimulating factor (GM-CSF), TNF-, IL-1, and interferon, can activate HIF-1 to inhibit neutrophil apoptosis (62, 63)

Its primary therapeutic effects are to invigorate spleen yang and soothe the liver to regulate qi

Pearson and Ledford, 2025[84])

GHK-Cu focuses on copper-mediated collagen synthesis and antioxidant activity valuable for skin and wound research, but absent the vascular and neuroprotective dimensions of the compounds profile