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Some patients may require imaging studies (ultrasound, CT scanning) or referral to hepatology, haematology, or oncology services

The secondary antibodies are highly cross-adsorbed Alexa Fluor Plus conjugates: Donkey anti-Rabbit IgG (H + L) 488 (Thermo Fisher Scientific, catalog: A32790), Donkey anti-Goat IgG (H + L) 647 (Thermo Fisher Scientific, catalog: A32849), and Donkey anti-Mouse IgG (H + L) 594 (Thermo Fisher Scientific, catalog: A32744)

Preclinical studies suggest it promotes angiogenesis (new blood vessel formation), collagen synthesis, and modulation of nitric oxide pathwayskey steps in tissue repair

Notably, RBD patients with hyposmia had higher levels of SAA positivity, which was also higher than DAT positivity, suggesting that alpha-synuclein SAA becomes abnormal before DAT imaging 98

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Silymarin in the Prevention and Treatment of Liver Diseases and Primary Liver Cancer