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Immediately after LPS injection, it decreased by 93% to a minimum at 2 h pi , after which it increased to more than double of the initial value at 24 h pi

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Alapati et al

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Hunter, 2008)

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Anyway, if it is true that a hyperoxic stimulus re-creates the benefits of a hypoxic-like response without inducing a detrimental hypoxic status, it still has yet to be proven that the benefit of this stimulus overwhelms the known harmful effects of hyperoxia although such a short time of exposure is not likely to enter toxic levels, especially in pathologic situations

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