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doi: 10.1161/HYPERTENSIONAHA.115.05315 142 YangZ.WangQ.LiuY.WangL.GeZ.LiZ.et al

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Genome Res 14 , 21622168 (2004)

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A meta-analysis of 15 randomized controlled trials showed modest BMI reduction with inositol supplementation, with the strongest evidence in PCOS populations where inositol improved insulin resistance and showed non-inferiority to metformin in 26 RCTs involving 1,691 patients