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Description
As previously discussed, RMECs are highly sensitive to ferroptosis under pathological conditions, as they poorly upregulate GPX4 and SLC7A11, while RPE cells resist ferroptosis via upregulating FTH1 and activating the Nrf2 antioxidant pathway (154)
Dimet-Wiley A, Wu Q, Wiley JT, et al
doi: 10.1016/j.neuron.2004.06.004
Embracing cancer complexity: hallmarks of systemic disease
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