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Description
Exposure of macrophages to pro-inflammatory stimuli results in decreased sirtuin levels associated with increased activation of RelA/p65 subunit of NF-kB and increased pro-inflammatory cytokine release (217)

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Our L-carnitine dose was 300 mg twice a day, which falls within the typical range of 250 3000 mg total dose per day across and within studies [ e.g
Porphyromonas gingivalis regulates atherosclerosis through an immune pathway
