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Madayag A, Lobner D, Kau KS, Mantsch JR, Abdulhameed O, Hearing M, et al

Flint J, Kendler KS

However, these combination effects are highly dependent on experimental models and co-administered components: synergistic metabolic improvements have been observed in animal studies (80), whereas some human studies report only modest reductions in liver enzymes without significant changes in broader metabolic parameters (64)

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Free or bioavailable testosterone and dihydrotestosterone (DHT) as the main testosterone metabolite followed the same trend (Fig