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Post-marketing data have also noted rare risks such as gallbladder disease, acute kidney injury in volume-depleted patients, and potential worsening of diabetic retinopathy during rapid glycaemic control [93]

In December 2024, the FDA approved the GLP-1 medication tirzepatide the active ingredient in a popular weight loss medication for the treatment of obstructive sleep apnea in individuals with obesity

Furthermore, a decreased number of bromine atoms on the phenyl moiety was associated with increased inhibitory activity

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After subcutaneous injection, they reach effective circulating concentrations relatively early, thus beginning to lower plasma glucose soon after initiating such treatment

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