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Chaudhary R, Liu B, Bensalem J, Sargeant TJ, Page AJ, Wittert GA et al (2022) Intermittent fasting activates markers of autophagy in mouse liver

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Potential reasons for the lack of immunotherapy response in HGSOC patients may include abundance of immunosuppressive factors in ovarian TME such as infiltration of a variety of immunosuppressive cells such as myeloid-derived suppressor cells (MDSC), cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAM) and Tregs