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First isolated in 1974 by Swiss researchers Schoenenberger and Monnier from the cerebral venous blood of rabbits during electrically induced slow-wave sleep, DSIP was the first endogenous peptide identified specifically in the context of sleep regulation

Brain sections from the scopolamine-AD group treated with galantamine (AD + GLA) (Figure 3I, 3J) showed astrocytes with large and thin ramified processes in-between the pyramidal cells CA3 region and granular cells in DG

doi: 10.1016/j.trsl.2007.07.002 9 ClausenT