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The released Fe 3+ is then reduced to Fe 2+ by six-transmembrane epithelial antigen of prostate 3 (STEAP3) and exported from the endosome into the cytoplasm by divalent metal transporter1 (DMT1)

[DOI] [PubMed] [Google Scholar] 13.Walker J.M., Tsivkovskii R., Lutsenko S

10.1016/j.acthis.2020.151677 11 AnthonsenS.LarsenJ.PedersenP

79,80 This phenomenon has been seen in patients with chronic kidney disease (CKD), and a phase II CKD cohort study found that plasma Leu and valine are significantly decreased in CKD patients compared with normal controls

doi: 10.3390/ijms25115782