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Description
ATP + H2O + monochlorobimane[side 1] ADP + phosphate + monochlorobimane[side 2] Substrates: - Products: -

NQO1, quinone dehydrogenase 1

Reactive oxygen species are free radicals generated during normal bio-physiological functions with unpaired electrons and there is evidence that excessive reactive oxygen species promotes carcinogenesis via raised oxidative stress and DNA mutation (Prasad et al

doi: 10.1002/mnfr.200700412

phthalic acid

In diabetes, chronic hyperglycaemia saturates this pathway early on, causing more than 30% of glucose to be metabolised through the polyol pathway [16,45]
