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Merrill, O.A

Berginer VM, Berginer J, Salen G, Shefer S, Zimmerman RD

The IRP-IRE regulatory system operates at the post-transcriptional level and is sensitive to cellular iron availability

The authors demonstrated that larger particles (5 m) caused more severe obstruction than smaller ones (2 m, 80 nm), suggesting size-dependent neurovascular toxicity

They include megaloblastic anemia, lethargy, failure to thrive, microcephaly, brain abnormalities, developmental delay, intellectual deficit, seizures, and retinopathy

The research indicates that there are underlying sex-specific differences in DNA methylation in both healthy as well as tumor-bearing states