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One major issue is their lack of selectivity, as they can carry NADs into almost all cell types

These findings suggested that DEG may not drive 2-HG formation, as occurs with decreased OGDHc function 22,24

The gene showed low activity in stationary macrophages (M0), increases in pro-inflammatory differentiated cells (M1 macrophages), and decreases in cells differentiating into anti-inflammatory macrophages (M2 macrophages) (69)

The most common site is the abdominal fat, a few inches to the side of the navel

It sounds like youve put a lot of time and effort into surviving and getting through that trauma, and its fairly clear how much its affected you in the aftermath