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Recent studies have demonstrated that even low-level lead exposure can impair sperm parameters, including motility and morphology, and disrupt hormonal balance, particularly testosterone production by targeting the HPG axis (15)

In vivo studies using the chick chorioallantoic membrane (CAM) assay confirm significant antiangiogenic activity, marked by downregulation of key angiogenic factors (VEGF, FGF2, and ANG1)

Research Use Cases: Research shows that Glutathione is widely used for its antioxidant properties and its role in detoxification

In this context it is noteworthy that IAA and IPA alone did not elicit any significant cytotoxic effect

Iron (Fe 2+ ) can be oxidized to Fe 3+ by the ferroxidase hephaestin (Heph) and bind to transferrin (TF) on cell membranes, forming the TF-Fe 3+ complex, which is facilitated by the presence of apo-Tf

This disruption of DNA replication and repair and HSP protein refolding can trigger mitotic arrest and even apoptosis when injury is severe