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The present review has collated the foremost categories of nutrients known to offer advantages in managing DED, encompassing EFAs, vitamins, trace elements, and phytochemicals, along with six additional groups of emerging nutrients supported by studies demonstrating their efficacy in alleviating symptoms of DED


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In contrast, the later phase of apoptotic cell death that consists of the destruction of nuclear deoxyribonucleic acid (DNA) (96, 113, 229, 483, 514518) and a cascade of caspase activation (65, 96, 130, 143, 347, 348, 405, 425, 483, 519) is not reversible

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