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It is widely believed that high concentration of GSH in the ER keeps protein disulfide isomerases (PDIs) in the reduced form [75]
12,13 Importantly, recent experience with 0936T in 2025 has been favorable and many claims have been paid
Therefore, 18 CF patients were scheduled for treatment with high doses of NAC (600, 800, and 1000 mg/day) three times a day, for a period of 4 weeks
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Shaking creates shear forces, rapid mechanical stress that breaks peptide bonds
doi: 10.1046/j.1471-4159.2001.00090.x
