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Also, we cannot rule out that new symptoms could appear later in the life of these children, or that current symptoms might be caused by other genetic defects, says King Saud bin Abdulaziz University for Health Sciences professor Majed Alfadhel.

doi: 10.1128/spectrum.01979-23 9 ChengS.-Y.JiangL.WangY.CaiW

Altered gut microbiota can signal through pattern recognition receptors on gut epithelial cells, activating the NF-B pathway and leading to changes in gut homeostasis [122]

In addition, high levels of intracellular Ca +2 and iron cause mitochondrial dysfunction, ROS generation, and ferroptosis [147]

S., Li, J., Dibona, M

Ascorbate has also been implicated in auxin catabolism and the synthesis of abscisic acid and gibberellins through its functions with different dioxygenases