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The capturing capacity of aptamer-loaded magnetic beads is not only dominated by the aptamer density coupled on the surface of magnetic beads but also by the steric hindrance among neighbored aptamers

doi: 10.1128/AEM.01259-15 73 RueppellO.ChristineS.MulcroneC.GrovesL

FIGURE 2 The important role played by A in AD pathogenesis led to the amyloid cascade hypothesis (Hardy and Higgins, 1992), based on the observation that early onset, familial forms of AD are associated with mutations in APP or presenilin 1 or 2 and that all appear to be associated with A generation, deposition, or aggregation propensity (Levy et al., 1990

The rate of this hydrolysis is influenced by factors such as pH, temperature, and the specific chemical structure of the imine bond, but in a neutral aqueous solution like PBS, it proceeds effectively, leading to the observed rapid degradation (Fig

Mu-Mosley H, Ostermann L, Zhao Y, Bonifant C, Gottschalk S, Velasquez MP, Andreeff M
HoloTC had a greater area under the ROC compared with serum B 12 concentrations (0.85 vs
