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Biofilm is defined as an assemblage of huge numbers of microbes of the same species in a common entity that is irreversibly associated with a surface i.e

Masuda et al

It is tasked with the recognition and neutralization of foreign antigenic entities and works in synergy with other physiological systems to ensure the maintenance of systemic stability and equilibrium

Acta Pharmacol Toxicol (Copenh) 30 , 3648 (1971)

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