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K.et al

Archives of Pediatrics & Adolescent Medicine, 156(9), 929-933

Frear RS

They also may justify additional diagnosis codes for peripheral neuropathy

As a result, defenses against ROS are activated 14 by an array of nonenzymatic antioxidants [metabolites such as ascorbate (AsA), carotenoids, glutathione (GSH) and proline] and antioxidant enzymes [such as guaiacol peroxidases (GPOX), catalase (CAT), superoxide dismutase (SOD) and AsA-GSH cycle enzymes like glutathione reductase (GR) ascorbate peroxidase (APX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR)], work together for detoxification of ROS 7,8,15,16,17,18,19,20

Elevated copper levels can also lead to a decrease in S-adenosylmethionine (SAMe) and glutathione levels, which can affect methylation and toxin removal from the body