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BR-deficient mutants ( d^im and bzr1 ) exhibited reduced pollen viability, pollen germination, and seed number, whereas overexpression of DWARF (DWF) or BRASSINAZOLE RESISTANT 1 (BZR1) had the opposite effects

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However, this meta-analysis was based on seven randomized control trials with heterogeneous methodology and a small sample size ( n = 245) and further studies are necessary to determine the potential impact of NAC on craving symptoms in SUD