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Description
The apyrimidinic endonuclease/redox effector factor (APE1) is an important enzyme for DNA-damaged base removal, and decreased APE1 levels in sensory neurons increase neurotoxicity in OIPN models, targeting APE1 by the small molecules APX3330 and APX2009

P., Hendrickx P
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As previously mentioned, lysine is one of only two amino acids that are degraded exclusively into ketones instead of glucose

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10.1007/s10123-018-0027-9 57 DianatM.SadeghiN.BadaviM.PanahiM.Taheri MoghadamM
