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By forming stable complexes with toxic metal ions, chelating agents facilitate their elimination from the body (Dehghan and Khoshkam 2012

doi:10.1016/j.brainres.2010.11.013 McCall KD, Holliday D, Dickerson E, Wallace B, Schwartz AL, Schwartz C, Lewis CJ, Kohn LD, Schwartz FL (2010) Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages

There are no hormone-related or testosterone-related effects

Experiments utilizing an obese mouse model demonstrated that the in vivo anti-inflammatory and insulin sensitizing effects of omega-3 PUFA are dependent on expression of FFAR4/GPR120

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Interestingly, decreased angiopoietin-2 was found exclusively in LC and could be a differentiation biomarker between LC and ME/CFS [199]