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6.1 Biomarkers of ferroptosis in ARDS The identification of reliable biomarkers is critical for diagnosing ferroptosis-driven ARDS, stratifying patients for treatment, and monitoring therapeutic responses

The kinds of evidence include both double-blind, placebo-controlled clinical trials (341) and observational (cross-sectional) studies in both humans (348,510512) and rodents (513)

Injections of B6 may also be given to patients with impaired gastrointestinal absorption

Beyond its well-documented inflammation regulation, antioxidant, and antibacterial properties, quercetin regulates sebum secretion, repairs the skin barrier, resists melanin and scarring, and interacts with a diverse array of molecular targets (Figures 1, 2)

These factors influence capillary permeability, thereby resulting in stromal edema, a hallmark of this phase of the cycle (Plaisier, 2011)

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