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Some afferent fibers with very high response thresholds before the experimental incision reduced their response threshold 1 h after the incision [17]

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Acid sphingomyelinase inhibition induces cerebral angiogenesis postischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism

They might review the frequency of your treatments or explore other factors that could be contributing to this reaction